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KMID : 0903520060490020129
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2006 Volume.49 No. 2 p.129 ~ p.134
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Antioxidant and Antibacterial Effects of Korean Isodon japonicus H.
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An Bong-Jeun
Park Jung-Mi
Bae Ho-Jung
Pyeon Jeong-Ran
Song Mi-Ae
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Abstract
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Biological activities and application of Isodon japonicus H. were investigated. In the physiological activities, the electron donating ability (EDA) was 66.3% in 100 ppm and SOD-like activity was as high as 85.0% in 1,000 ppm with gradual increase. As for the inhibitory effect of xanthine oxidase, it was 70.0% in 1,000 ppm and as low as 40.0% in 500 ppm; also, as for the inhibitory effect of tyrosinase, it was as low as 20.5% below 1,000 ppm. The tyrosinase inhibition effect related to skin whitening function showed 30.0% at 1,000 ppm level or below, indicating a relatively low effect. As for the result of measuring the lipid oxidation, all the concentrations of medical ion treatments showed anti-acidification ability; also, as for the metal ion blocking effects against the lipid oxidation promoting factors (Fe2+ and Cu2+), Fe2+ was better than Cu2+ and all concentrations of medical ion treatments was 60.0% in 100 ppm. Also, the clear zone against various bacteria at 0.5 and 1.0 mg/disc was clearly shown. When it was applied into a normal skin-softener, it was safe, showing its potential as a natural material of cosmetics.
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KEYWORD
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Isodon japonicus, antioxidant, antibacterial
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